The Leica TP1020 Automatic Tissue Processor

Automation Grade Automatic
Model Name/Number TP1020
Sterile/ Non Sterile Sterile
Brand Leica
Usage/Application Hospital
Nominal frequency 50/60 Hz
Nominal voltage 100/120/230/240 V AC +- 10%
Type Tissue Processor
Height 595 – 780 mm
Diameter of rollers 610 mm

The Leica TP1020 Automatic Tissue Processor:-

A Workhorse for Histology Labs

The Leica TP1020 Automatic Tissue Processor is a powerful and versatile instrument designed to streamline and automate the process of preparing tissue samples for microscopic examination in histology labs. This in-depth description delves into the functionalities, benefits, and technical specifications of the TP1020, making it a valuable resource for both experienced technicians and those new to tissue processing.

Understanding Histology and Tissue Processing

Histology is the study of tissues at a microscopic level. To prepare tissues for this analysis, they undergo a multi-step process involving fixation, dehydration, clearing, and paraffin wax infiltration. The TP1020 automates these steps, ensuring consistent and reliable results while minimizing human error.

  • Fixation: Tissues are treated with chemicals (fixatives) to preserve their structure and prevent them from decomposing.
  • Dehydration: The fixative and water are removed from the tissues by gradually increasing concentrations of alcohol.
  • Clearing: Alcohols are replaced with a solvent (typically xylene) that allows paraffin wax to penetrate the tissue.
  • Paraffin Wax Infiltration: The tissues are infiltrated with molten paraffin wax, which solidifies to create a supportive medium for sectioning.

The TP1020 in Action: A Step-by-Step Guide

  1. Sample Preparation: Tissue samples are collected during surgery or biopsy procedures and placed in embedding cassettes. These cassettes hold the tissues in place throughout the processing run.
  2. Loading the TP1020: The cassettes containing the tissues are loaded into a basket within the TP1020. The instrument offers the flexibility to accommodate one or two baskets depending on workload requirements.
  3. Reagent Stations: The TP1020 features ten stations that can be filled with various reagents needed for tissue processing, including fixatives, alcohols, solvents, and paraffin wax. An optional eleventh station can be used for a third paraffin wax bath.
  4. Processing Modes: The TP1020 boasts both manual and automatic processing modes. In manual mode, the user controls the movement of the tissue basket through the stations and determines processing times. Automatic mode allows pre-programmed processing protocols to be executed, ensuring consistent and standardized results. The TP1020 comes with nine pre-defined programs that can be customized to meet specific laboratory needs.
  5. Tissue Agitation: To ensure thorough penetration of reagents and optimal tissue infiltration, the TP1020 agitates the tissue basket as it moves through each station. This agitation can be switched off if desired for delicate tissues.
  6. Power Outage Protection: A unique feature of the TP1020 is its ability to protect specimens even during power outages. In the event of a power failure, the tissue basket automatically submerges into the current station, preventing tissues from drying out. Once power is restored, processing resumes from the interrupted point.
  7. Safety Features: The TP1020 prioritizes user safety. It complies with stringent safety regulations and offers optional fume control systems to remove hazardous fumes produced by some reagents. The instrument also features an excess temperature cut-out to prevent overheating.

Benefits of the Leica TP1020

  • Enhanced Workflow Efficiency: Automating the tissue processing workflow saves valuable time for lab personnel, allowing them to focus on other critical tasks.
  • Improved Tissue Quality: Consistent and controlled processing conditions ensure optimal tissue preservation and morphology, leading to more accurate diagnoses.
  • Standardized Results: Pre-programmed processing protocols minimize variability and ensure consistent results across different batches.
  • Reduced User Error: Automation minimizes human intervention, reducing the risk of errors associated with manual processing.
  • Increased Laboratory Throughput: The TP1020’s capacity to handle variable workloads, with options for single or double tissue baskets, allows labs to process a higher volume of samples efficiently.
  • User-Friendly Operation: The intuitive control panel and LCD display make the TP1020 easy to learn and operate, minimizing training time for new users.
  • Safety and Security: The TP1020 prioritizes user safety with features like fume control and temperature control. The instrument’s robust design ensures reliable operation.

Customization Options

The TP1020 offers various configuration options to cater to individual laboratory needs. These include:

  • Vacuum Function: Vacuum can be applied to any station during processing, accelerating tissue infiltration and reducing processing times.
  • Fume Control System: This system removes hazardous fumes generated by certain reagents, enhancing laboratory air quality and user safety.
  • Chloroform Compatibility: The TP1020 can be configured for use with chloroform, a solvent used in some specialized protocols.
  • Accessories: A variety of accessories are available to enhance the functionality of the TP


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